Monday, November 10, 2014

The results of studies on the long-awaited therapy without interferon impressed the largest interna


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Unica.md> Health> News> New hepatitis C drug will come to market later this year
The results of studies on the long-awaited therapy without interferon impressed the largest international congress for the study of Liver (International Liver Congress - ILC), held in April 2014 in London.
,, Antiviral drugs that act directly on the virus "(direct-acting antivirals - DAA), administered only orally, were the major interest in the research presented.
Doctors call these remedies "antivirals that act directly on the virus" csuivi (direct-acting antivirals) or "interferon-free", ie without interferon and therefore important (!) Without its side effects.
DAA class preparations (Sofosbuvir, Daclatasvir, Ledipasvir, Ombitasvir, Simeprevir) basically blocks hepatitis C virus multiplying in the body by direct action without affecting the immune csuivi system, as did the treatments so far.
In studies SAPPHIRE-I-II TURQUOISE, PEARL-III, patients previously untreated chronically infected HCV genotype GT1, the most common and most difficult to cure, received treatment with DAA plus / without ribavirin for 12 weeks, after which the rate of sustained virological response (Sustained Virologic Response - SVR12) was 91.8 to 96.2%.
"All these studies csuivi on the efficacy and safety of healing patients with liver disease using DAA class preparations are encouraging," said Dr. Allesio Aghemo at the University of Milan.
Several pharmaceutical companies will launch on the market until later this year and early next year so revolutionary medicines and ,, new treatment administered orally in a single dose daily for 12 weeks, will heal at a rate of almost 100% of hepatitis C, '' said Graham csuivi R. Foster Professor of Hepatology, University "Queen Mary" in Congress in London.
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